Luliconazole Cream is a topical antifungal agent used to treat fungal infections
Luliconazole Cream Uses.
Luliconazole is indicated for the treatment of interdigital tinea pedis, tinea cruris, or tinea corporis infections caused by Trichophyton rubrum and Epidermophyton floccosum.
Pharmacodynamics
Luliconazole kills the organisms Trichophyton rubrum and Epidermophyton floccosum, most likely by altering their fungal cell membranes.
Mechanism of action
The exact mechanism of action for luliconazole’s anti-fungal activity is still not known, but Luliconazole Cream is thought to inhibit the enzyme lanosterol demethylase. Lanosterol demethylase is needed for the synthesis of ergosterol, which is a major component of the fungus cell membranes.
Absorption
Although luliconazole is administered topically.
Volume of distribution
The volume of distribution was not quantified.
Protein binding
Plasma protein binding of luliconazole is >99%.
Metabolism
The metabolism of Luliconazole has yet to be determined.
Route of elimination
The route of elimination of Luliconazole Cream has yet to be determined.
Half-life
The half life of Luliconazole has yet to be determined.
Clearance
The clearance of Luliconazole has yet to be determined.
Toxicity
In clinical trials, no serious toxicity was reported, only local irritation (mild contact dermatitis and cellulitis) at the site of application was found.